ACR Responder Criteria
DefinitionThis section has been translated automatically.
Rheumatological effectiveness parameter of the American College of Rheumatology (ACR20-ACR70) for measuring the success of therapy, which has become generally accepted, especially in clinical studies.
General informationThis section has been translated automatically.
- The ACR response criteria evaluate whether the therapy has led to an improvement of predefined symptoms. An ACR20 efficiency is present, for example, if the patient has experienced at least 20% improvement of the following parameters compared to the initial value:
- Number of sensitive/painful joints
- Number of swollen joints
- In addition, 3 of the following 5 parameters must show an improvement of > 20% compared to the initial value:
- physician's global assessment of the arthritic condition
- Patient's global assessment of the arthritic condition
- Pain (visual analogue scale (VAS)
- HAQ functional disability index (HAQ)
- CRP value (CRP, S-reactive protein).
LiteratureThis section has been translated automatically.
- Felson DT, Anderson JJ (2001) A review of evidence on the discriminant validity of outcome measures in rheumatoid arthritis. J Rheumatol 28: 422-426