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DefinitionThis section has been translated automatically.
The attachment of an acetyl group to a molecule is called acetylation in organic chemistry. The acetylation of a protein is catalysed by enzymes (acetylases). The cleavage of the acetyl group, the deacetylation, is catalysed by deacetylases (also deacetylases). Acetylation by N-acetyltransferases 1 and 2 plays an important role in the metabolism (detoxification) of drugs or contact allergens (e.g. phenylenediamine) (see below N-acetyltransferases and their coding genes NAT1 and NAT2).
Prof. Dr. med. Peter Altmeyer