Poloxamines

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Poloxamines are a subgroup of the poloxamers (see below poloxamers). Like the poloxamers, they are block polymers (copolymers in which two longer blocks of a monomer follow each other: AAAAAAAAABBBBBBBBBBBBBB...), structurally composed of an ethylenediamine nucleus whose amino groups are substituted with copolymers of polyoxyethylene and polyoxypropylene blocks of variable length. These are non-ionic surfactants.

Occurrence
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Various poloxamines are used in medical (e.g. in contact lens fluids) and cosmetic formulations. Poloaxmines act as emulsifiers. The following poloxamines are listed according to the INCI nomenclature:

  • Poloxamines 1101 (INCI)
  • Poloxamine 1102 (INCI)
  • Poloxamine 1104 (INCI)
  • Poloxamine 1301 (INCI)
  • Poloxamine 1302 (INCI)
  • Poloxamine 1304 (INCI)
  • Poloxamine 1307 (INCI)
  • Poloxamine 1501 (INCI)
  • Poloxamine 1502 (INCI)
  • Poloxamine 1504 (INCI)
  • Poloxamine 1508 (INCI)
  • Poloxamine 304 (INCI)1
  • Poloxamine 701 (INCI)
  • Poloxamine 702 (INCI)
  • Poloxamine 704 (INCI)
  • Poloxamine 707 (INCI)
  • Poloxamine 901 (INCI)
  • Poloxamine 904 (INCI)
  • Poloxamine 908 (INCI)

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Last updated on: 29.10.2020