Allergy test; Allergy testing; Prick test
DefinitionThis section has been translated automatically.
Test for the diagnosis of an IgE-mediated allergic reaction of the immediate type ( type I allergy) with allergen test solutions on the skin; to be performed in case of a negative or doubtful rub or scratch test and before performing the intradermal test.
ImplementationThis section has been translated automatically.
After applying the allergen test solutions to the skin on the forearm flexion side (more rarely on the back), the skin is lightly incised at these points with a blood lancet or prick needle and lifted slightly without causing bleeding. A positive control (0.1% histamine solution) and a negative control (0.9% NaCl solution) should be tested to exclude false negative and false positive reactions. The urticarial reaction is read after 20 minutes. According to the diameter of the wheal and reflex erythema compared to the positive and negative control, the respective test reactions are evaluated semi-quantitatively from 0 to ++++.
Note(s)This section has been translated automatically.
Local and systemic allergic type I reactions can occur in rare cases (especially in the case of improper testing, high sensitization and concentrated test solutions, e.g. for drugs). S.a. Provocation test.
ROXALL has recently introduced an automatic pricking machine (PRIXI) which, when the arm is correctly positioned, performs the pricking process automatically within 15 seconds. The economic efficiency will be demonstrated.
LiteratureThis section has been translated automatically.
- Bodtger U et al (2003) Long-term repeatability of the skin prick test is high when supported by history or allergen-sensitivity tests: a prospective clinical study. Allergy 58: 1180-1186
- Darsow U et al (2003) Atopic patch test. Atopic eczema and allergy. dermatologist 54: 930-936
- Ring J (1988) Applied allergology. 2nd edition. MMW Publishing House, Munich
- Sander I et al (2004) Comparison of wheat and rye flour skin prick test solutions for diagnosis of baker's asthma. Allergy 59: 95-98