Med

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.04.2021

Dieser Artikel auf Deutsch

Synonym(s)

Erythema dose minimum; Minimum erythema dose

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

The erythema threshold of ultraviolet light, or UV radiation, is the weakest, but still (usually sharply) distinguishable skin redness from the non-irradiated environment, which can be read 7 or 24 hours after the test irradiation.

General informationThis section has been translated automatically.

First described by von Wucherpfennig in 1931.

IndicationThis section has been translated automatically.

Light dermatoses or in the case of UV-provocable dermatoses(persistent light reaction, photoallergic eczema or phototoxic dermatitis, light urticaria, lupus erythematosus, protoporphyria erythropoetica, Hidroa vacciniformia, polymorphic light dermatosis etc.) by a possibly reduced MED-UVB or MED-UVA. See also photo patch test and photo provocation test.

ImplementationThis section has been translated automatically.

In accordance with the exponential progression of the UV reaction on the skin, a series of previously non-UV exposed test fields (5-8 small areas on the buttocks or back) are exposed to geometrically or arithmetically increasing irradiation times or energy quantities to determine the MED-UVB and MED-UVA and read and evaluated according to the above definition. Information on normal values or reference ranges for MEDs must always be seen strictly in the context of the methods used; in particular, the irradiation spectra used are of crucial importance. A comparability of MEDs based on different irradiation sources can be achieved by conversion to the standard erythema dose (SED).

LiteratureThis section has been translated automatically.

  1. Gambichler et al (2006) Reference limits for erythema-effective UV doses. Photochemical photobiol 82: 1097-1102
  2. Wucherpfennig V (1931) Biology and practical applicability of the erythema threshold of UV. Radiotherapy 40: 201-243

TablesThis section has been translated automatically.

Test location

Non-exposed skin region (buttocks)

Test Fields

1.5 x 1.5 cm

Radiation sources

UV-A1: Metal halide lamp (340-400 nm)

UV-B: Fluorescent lamp (Philips TL12: 285-350 nm)

UV dosages

UV-A1: skin type I/II: 5, 10, 15, 20, 25, 30 J/cm2

UV-A1: skin type III/IV: 20, 25, 30, 40, 60, 80 J/cm2

UV-B: skin type I/II: 25, 50, 75, 100, 125, 150 mJ/cm2

UV-B: skin type III/IV: 75, 100, 125, 150, 175, 200 mJ/cm2

Reading

immediately and after 24 hours.

Authors

Last updated on: 29.04.2021

Author: Prof. Dr. med. Peter Altmeyer