Persistent light reactionL57.8

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Chronic light allergy; Persistent light allergy; Persistent light reaction; Persistent photoallergy

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DefinitionThis section has been translated automatically.

Subtype of chronic actinic dermatitis (CAD), which develops from a long-standing sensitivity to light and is triggered by pre-existing sensitization without further photoallergen administration in the presence of possibly low light exposure. Decrease of MED in the UVA and UVB range.

EtiopathogenesisThis section has been translated automatically.

Unclear, mostly primarily photosensitization with persistence of the photoallergen (e.g. olaquindox). Later on the skin symptoms may be triggered and maintained by low light doses.

ManifestationThis section has been translated automatically.

Occurs mainly in middle-aged and older men.

LocalizationThis section has been translated automatically.

Areas of the body exposed to light, especially the forehead, cheeks, auricles, neck, throat, back of the hands.

Clinical featuresThis section has been translated automatically.

Initially acute dermatitis, later recurrent course with transition to a chronic stage. Inflamed, red to livid, pad-like thickened, furrowed, scaly, occasionally weeping skin changes. Considerable lichenification, often excruciating itching. The skin lesions are clearly demarcated from the unexposed skin, whereby this transition is not sharply defined in lines, but irregularly loosened. The skin changes persist for months after low UV exposure, can subside in winter and exacerbate again in spring after brief UV exposure. The maximum variant of chronic actinic dermatitis is called actinic reticuloid (see below chronic actinic dermatitis).

Differential diagnosisThis section has been translated automatically.

TherapyThis section has been translated automatically.

ProphylaxisThis section has been translated automatically.

Note(s)This section has been translated automatically.

The actinic reticuloid is considered the maximum variant of chronic actinic dermatitis.

LiteratureThis section has been translated automatically.

  1. Dawe RS (2003) Diagnosis and treatment of chronic actinic dermatitis. Dermatol Ther 16: 45-51
  2. Lehmann P et al (2011) Light dermatoses: Diagnosis and overview. Dt Ärztebl 108: 135-141
  3. Ling TC et al (2003) Treatment of polymorphic light eruption. Photodermatol Photoimmunol Photomed 19: 217-227
  4. Mang R et al (2003) Sun protection during holidays. dermatologist 54: 498-505
  5. McCall CO (2003) Treatment of chronic actinic dermatitis with tacrolimus ointment. J Am Acad Dermatol 49: 775
  6. Wolf C et al (1988) The syndrome of chronic actinic dermatitis. Dermatologist 39: 635-641
  7. Yap LM et al (2003) Chronic actinic dermatitis: A retrospective analysis of 44 cases referred to an Australian photobiology clinic. Australas J Dermatol 44: 256-262

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Last updated on: 29.10.2020