DefinitionThis section has been translated automatically.
IL31 (interleukin-31) is a protein-coding gene located on chromosome 12q24.31. Signaling pathways include innate immune system and Th2 differentiation (Dillon SR et al. 2004).
General informationThis section has been translated automatically.
The encoded protein, the cytokine IL31, is mainly produced by activated T cells of the type Th2 and is produced by epithelial cells, interacts with a heterodimeric receptor consisting of IL31RA and OSMR and is constitutively expressed on epithelial cells. For further information on IL-31 see there.
LiteratureThis section has been translated automatically.
- Dillon SR et al (2004) Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nature Immun. 5: 752-760.
