Disodium cromoglicic acid

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Cromolyn

Definition
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Antiallergic, mast cell stabilizer.

Half-life
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1,4 h

Indication
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Rhinitis allergica, conjunctivitis allergica, bronchial asthma, food allergy.

Limited indication
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Pregnancy.

Dosage and method of use
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  • Adults: 4 times/day 2 capsules p.o., children from 2 to 4 years: 4 times/day 1 capsule p.o.
  • Nasal spray: 4 times/day 1 spray in each nostril
  • Dosing aerosol: 4-8 times/day 2 sprays per inhalation
  • Eye drops: instill 1 trp. 4 times/day.

Standard concentration
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Nasal spray, eye drops: 2%, dosing aerosol: 1 mg/spray burst.

Undesirable effects
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Bronchospasm, eosinophilic lung infiltrate, eosinophilia, gastrointestinal disorders (gastroenteritis in 1-3% of patients), micturition disorders, allergic reactions, pericarditis, headaches, myalgias, arthralgias.

Interactions
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No interactions are known for disodium cromoglicic acid.

Contraindication
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Pneumonia, hypersensitivity to active ingredients and auxiliary materials.

Preparations
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Acechromol, Colimune cps., Cromolind, Diffusyl, DNCG, Intal, Pediachrome, Pulbil, Vividrin

Patientinformation
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Patients should be informed that the effect of DNCG only occurs with long-term consistent application (i.e. after 2 weeks at the earliest) and that frequent regular application (4 times/day) is necessary!

Incoming links (2)

Cromolyn; Quercetin;

Outgoing links (1)

Antiallergics;

Authors

Last updated on: 29.10.2020