Chemotaxis

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Influence of certain chemical stimuli (messenger substances - chemokines) on the movement of cells (cells of the immune system, bacteria, gametes) If the cells move towards the chemical stimulus (the higher concentration of a chemokine), this is called positive chemotaxis, and the opposite is called negative chemotaxis.

A chemotactic agent with a positive influence is called an attracting agent, while one with a negative influence is called a repellent.

Different groups of substances function as chemokines (also known as chemotactics). Known chemokines are:

  • Components of the complement system
  • Cytokines
  • Components of the bacterial cell membrane (e.g. peptidoglycans)
  • Leucotrienes
  • Amino acids
  • Sex pheromones

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CXCL10 gene;

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Last updated on: 29.10.2020