Central supramolecular activation cluster

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Synonym(s)

cSMAC

Definition
This section has been translated automatically.

During activation of T cells by antigen-presenting cells (APZ), a complex structure is formed at the contact zone. Analogous to neuronal synapses, this structure has been termed a mature "immunological synapse" (IS). It consists of an inner activation area, cSMAC (central supramolecular activation cluster). In cSMAC the T-cell receptor, the accessory receptor CD28 and a protein kinase accumulate.

Incoming links (1)

Csmac;

Outgoing links (1)

Antigen-presenting cells;

Authors

Last updated on: 29.10.2020