Butylhydroxyanisole

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Butylhydroxianisole; CAS No 25013-16-5; INCI designation: BHA

Definition
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Antioxidant. In cosmetics, externally applied drugs, food (E320), plastics and rubber products

Field of application/use
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Butylhydroxianisole is mainly added to cereals and cereal products. Isolated contact allergic reactions, chronic urticaria and contact urticaria have been described. For a provocation test doses of 100 mg are recommended.

Literature
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  1. Barberis CL et al (2014) Hydrolytic enzymes production by Aspergillus section Nigri in presence of butylated hydroxyanisole and propyl paraben on peanut meal extract agar. Rev Iberoam Micol 31:131
  2. Goodman DL et al (1990) Chronic urticaria exacerbated by the antioxidant food preservatives, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). J Allergy Clin Immunol 86:570-575.
  3. Hannuksela M et al,(1986) Peroral challenge tests with food additives in urticaria and atopic dermatitis. Int J Dermatol 25:178-180.
  4. Le Coz CJ et al (1998) Contact dermatitis from tertiary-butylhydroquinone in a hair dye, with cross-sensitivity to BHA and BHT. Contact dermatitis 39:39-40
  5. Simon RA (1995) Food and Drug additives. Immunol. All Clin N America 15: 489-527

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Last updated on: 29.10.2020