Synonym(s)
1,2-benzisothiazolin-3-one; Sodium salt
DefinitionThis section has been translated automatically.
Widely used biocide and technical preservative with microbicidal and fungicidal action.
General informationThis section has been translated automatically.
- Used as a preservative in emulsion paints, varnishes, adhesives, detergents, fuels and in paper production. The dosage is 200-400 ppm depending on the area of application and combination with other biocides.
- Gloves made of polyvinyl chloride (PVC) often contain benzisothiazolinone (mostly in low concentrations < 50-250 ppm) and may cause contact allergies. Here, occlusion probably plays a decisive role in triggering the contact allergy.
- In case of clinical suspicion an epicutaneous test should be performed.
LiteratureThis section has been translated automatically.
- Aalto-Korte K et al (2006) Antimicrobial allergy from polyvinyl chloride gloves. Arch Dermatol 142: 1326-133
Kaur-Knudsen D et al (2012) Systemic allergic dermatitis following airborne exposure to 1,2-benzisothiazolin-3-one. Contact dermatitis 67:310-312
Prof. Dr. med. Peter Altmeyer