1,3-diphenylguanidine

Vulcanization accelerator in the manufacture of rubber products. 1,3-diphenylguanidine is included in the following epicutaneous test series: rubber (epicutaneous test series); leather and shoes (epicutaneous test series). It also plays an important role in occupational dermatology through its"latex allergy".

1. Dahlin J et al (2014) Triphenylguanidine, a new (old?) rubber accelerator detected in surgical gloves that may cause allergic contact dermatitis. Contact dermatitis 71:242-246
2. Hansson C et al (2014) Reaction profile in patch testing with allergens formed during vulcanization of rubber. Contact dermatitis 70: 300-308
3. Pacheco D et al (2013) Polysensitisation to rubber additives and dyes in shoes and clothes. Allergol Immunopathol (Madr) 41: 350-352