Raynaud's diseaseI73.0

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Primary Raynaud's syndrome; Raynaud's disease

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HistoryThis section has been translated automatically.

Raynaud, 1862

DefinitionThis section has been translated automatically.

Primary Raynaudian phenomenon. Negative variant: digitus mortuus.

Remark: Basically the clinical symptoms of Raynaud's disease (synonymous with "primary Raynaud's syndrome") do not differ from those of Raynaud's syndrome and are treated and updated under this comprehensibility.

EtiopathogenesisThis section has been translated automatically.

Idiopathic, triggers: Cooling stimulus, especially temperatures around 12-16 °C, endocrine factors: dysfunction of the thyroid and pituitary gland, frequent familial occurrence.

ManifestationThis section has been translated automatically.

Occurs in early adulthood, especially in women.

LocalizationThis section has been translated automatically.

Especially the index and middle fingers are affected.

Clinical featuresThis section has been translated automatically.

Symmetrical seizures in three stages, accompanied by paresthesia, numbness, tingling and burning sensation and pain at the transition from cyanosis to redness.
  • Phase 1: Paleness of one or more fingers.
  • Stage 2: Cyanosis.
  • Stage 3: Redness due to reactive hyperemia.
The individual phases may vary in severity. Duration of the attack: about 10 minutes in mild cases and initial stages, 30 to 120 minutes in severe cases or later stages.
  • In the chronic stage dystrophic skin of the affected fingers, nail dystrophy, wound healing disorders. The formation of symmetrical necroses limited to the fingertips, ranging from symmetrical to pinhead-sized necroses, is possible.

DiagnosisThis section has been translated automatically.

Clinic, nail fold capillaroscopy, pulse oscillography with cold provocation.

Differential diagnosisThis section has been translated automatically.

TherapyThis section has been translated automatically.

According to the Raynaudian phenomenon.

Progression/forecastThis section has been translated automatically.

Recurrent course. Development of sclerodactyly is possible.

LiteratureThis section has been translated automatically.

  1. Raynaud AGM (1862) De l'asphyxie locale et de la gangrène symétrique des extrémités. Doctoral thesis, Rignoux, Paris
  2. Raynaud M (1888) On asphyxia and symmetrical gangrene of the extremities 1862 and new researches on the nature and treatment of local asphyxia of the extremities 1874 Translated by T. Barlow In: Selected Monographs, New Sydenham Society, London, S. 1-199

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Last updated on: 29.10.2020