Ribis nigri folium
Synonym(s)
DefinitionThis section has been translated automatically.
The medicinally used dried, whole or cut leaves of the blackcurrant, obtained shortly after the flowering of the plant. Positive ESCOP monographs are available for this drug.
HMPC mon ograph: traditional-use: aching limbs, increase urinary output, flushing of the urinary tract, supportive for mild urinary symptoms.
ESCOP monograph: rheumatic diseasesCommission
E: not edited
IngredientsThis section has been translated automatically.
0.5 % flavonoids, especially kaempferol and quercetin. Furthermore tanning agents, essential oil with cymol and vitamin C.
EffectsThis section has been translated automatically.
A wide range of health effects such as antioxidant, anti-inflammatory, cytoprotective effects can be demonstrated. The drug has a slightly diuretic and hypotensive effect (study results are missing). There is also evidence of a broad antimicrobial spectrum, ranging from C.albicans, S.aureus, E.coli and E.faecium to influenza viruses. In cell cultures, extracts of Ribris nigri folium (arabinogalactan) lead to an increase in proliferation of keratinocytes and fibroblasts.
Field of application/useThis section has been translated automatically.
According to ESCOP guidelines, the drug is indicated for rheumatic complaints.
DosageThis section has been translated automatically.
3-4g of the drug as a tea infusion, 3 times a day; duration of use no longer than 2-4 weeks.
ContraindicationThis section has been translated automatically.
No reliable data for pregnancy and lactation and for children and adolescents under 18 years.
Allergy to one of the ingredients
InteractionsThis section has been translated automatically.
WW and UAW are not known. In rare cases hypersensitivity to the active substances may occur.
LiteratureThis section has been translated automatically.
- Feng C et al.(2016) Antioxidant capacities and anthocyanin characteristics of the black-red wild berries obtained in Northeast China. Food Chem 204:150-158.
- Haasbach E et al. (2014) Antiviral activity of Ladania067, an extract from wild black currant leaves against influenza A virus in vitro and in vivo. Front Microbiol 5:171.
- Miladinović B et al.,(2014) Chemical profile and antioxidant and antimicrobial activity of juices and extracts of 4 black currants varieties (Ribes nigrum L.). J Food Sci 79:C301-309.
- Nanashima N et al.(2015) Phytoestrogenic activity of blackcurrant (Ribes nigrum) anthocyanins is mediated through estrogen receptor alpha. Mol Nutr Food Res 59:2419-2431.
- Nowak A et al.(2016) Polyphenolic extracts of cherry (Prunus cerasus L.) and blackcurrant (Ribes nigrum L.) leaves as natural preservatives in meat products. Food Microbiol 59:142-149.
- Vagiri M et al. (2015) Phenolic compounds in blackcurrant (Ribes nigrum L.) leaves relative to leaf position and harvest date. Food Chem 172:135-142.
- Zippel J et al.(2009) A high molecular arabinogalactan from Ribes nigrum L.: influence on cell physiology of human skin fibroblasts and keratinocytes and internalization into cells via endosomal transport. Carbohydr Res 344:1001-1008.
- https://arzneipflanzenlexikon.info/index.php?en_pflanzen=120
- https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-ribes-nigrum-l-folium_en.pdf