Evidence-Based Phytotherapy

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 23.02.2024

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Synonym(s)

Rational Phytotherapy

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DefinitionThis section has been translated automatically.

Rational phytotherapy is based on traditional European phytotherapy. It defines the claim to use scientific evaluation standards alongside existing empirical data (empirical medicine) in order to prove the efficacy of the plants contained as well as the preparations and combinations on the basis of studies.

Rational phytotherapeutics(phytopharmaceuticals) are medicinal products which, in contrast to chemically defined medicinal products and isolated pharmacologically defined pure herbal substances (e.g. azelaic acid, ciclosporin, penicillins, etc.), contain herbal preparations, predominantly standardized and/or normalized extracts, as active ingredients (Loew 1999).

The entire extract (or combination of extracts) and thus a mixture of multiple substances is regarded as the active pharmaceutical ingredient.

It is postulated that each extract contained in a rational phytopharmaceutical has been proven to contribute to clinical efficacy.

If the phototherapeutic agent contains an extract of one or more drug parts of the same medicinal plant as the active ingredient, it is declared as a monopreparation. The extract is the active substance.

If the phototherapeutic agent in extract form contains several combination partners from different medicinal plants, it is declared as a herbal combination preparation.

Rational phytotherapy therefore differs fundamentally from therapy with synthetic active ingredients, which are administered as individual substances and whose singular effects are known. Herbal preparations can be obtained as pressed juices, oil macerates from fresh plants, powders from cut or crushed dried drugs. Extracts are extracts obtained by means of solvents, fractionation or by eliminating undesirable constituents. Phytotherapeutics are offered in conventional dosage forms such as drops, tablets, coated tablets or capsules.

General informationThis section has been translated automatically.

Rational phytotherapy claims to apply the same scientific methods to the phytopharmaceuticals administered as to synthetic medicines. It is based on the guidelines of Good Clinical Practice, with reliable pharmacological and toxicological studies, as well as proof of efficacy in randomized, controlled double-blind studies.

LiteratureThis section has been translated automatically.

  1. Colalto C (2018) What phytotherapy needs: Evidence-based guidelines for better clinical practice. Phytother Res 32: 413-425

  2. Fürst R et al. (2015) Evidence-Based Phytotherapy in Europe: Where Do We Stand? Planta Med 81(12-13):962-967.
  3. Loew D et al. (1999) Phytopharmacareport. Steinkopff Verlag Darmstadt p 7.

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Last updated on: 23.02.2024