Scopolamine patches

Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Scopolamine is a muscarinic receptor antagonist (parasympatholytic), belladonna alkaloid with a tertiary nitrogen group and a molar mass of 303.35 g-mol-1 and an average half-life of about 1.5 h. Together with atropine it occurs naturally in the nightshade plants belladonna, henbane and thorn-apple (tropane alkaloids). Scopolamine is highly soluble in water, especially in hot ethanol (Roth L 1984). Muscarinic receptor antagonists with a tertiary nitrogen group act both in the periphery and in the CNS (Graefe KH 2016). Scopolamine is used as a transdermal patch to prevent the symptoms of travel or seasickness such as dizziness, nausea and vomiting.

LiteratureThis section has been translated automatically.

  1. Graefe KH et al muscarinic receptor antagonists. In: Graefe KH et al (Eds) Pharmacology and Toxicology. Georg Thieme Publisher Stuttgart S.114-115
  2. Roth L et al (1984) Scopolamine. In: Roth L et al. (Eds) Poisonous plants, plant toxins. Nikol Publishing Company Hamburg p.921

Last updated on: 29.10.2020