Eskape

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Acronym for multi-resistant bacteria (MRE), which frequently occur in nosocomial infections (Santajit S et al. 2016). This includes the following bacteria (Pendleton JN et al. 2013):

  • Enterobacteriaceae: multiresistant through the formation of extended spectrum β lactamases (ESBL) or carbapenemases
  • Staphylococcus aureus, methicillin-resistant(MRSA)
  • Klebsiella pneumoniae with formation of carbapenemases
  • Acinetobacter spp., multi-resistant
  • Pseudomonas aeruginosa, multi-resistant
  • Enterococci, especially E. faecium with and without vancomycin resistance(AER)

Note(s)This section has been translated automatically.

Recently it has been proposed to change the acronym "ESKAPE" to "ESCAPE": Klebsiellae should be grouped under "E" with other enterobacteria. Instead, Clostridium difficile ("C") should be included due to:

  • its virulence,
  • the rapid spread and
  • the high relapse rates after successful therapy

be included in the definition.

LiteratureThis section has been translated automatically.

  1. Pendleton JN et al (2013) Clinical relevance of the ESKAPE pathogens. Expert Rev Anti Infect Ther 11:297-308.
  2. Santajit S et al (2016) Mechanisms of Antimicrobial Resistance in ESKAPE pathogens. Biomed Res Int 2016:2475067.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer