Crb-65
Synonym(s)
DefinitionThis section has been translated automatically.
CRB-65 is the acronym for a clinical score that can be used to quickly assess the severity of outpatient acquired pneumonia.
The individual letters stand for:
- C = Confusion: Pneumonia-related confusion (disorientation to place, time or person)
- R = Respiratory rate: > 30/min
- B = Blood pressure: > 90/60mmHG
The value defines a statistical probability of death from pneumonia.
One point is indexed for each criterion determined, the maximum number of points is 4.
General informationThis section has been translated automatically.
Patients with a CRB score of 0 (no significantly increased mortality rate) can be treated as outpatients. For outpatient treatment, a "second look" should be arranged after 24-48 hours.
For patients with a CRB score of 1-2 (mortality rate 5%), inpatient admission is recommended.
Intensive therapy is necessary for patients with a CRB score of 3-4 (mortality rate > 20%).
Note(s)This section has been translated automatically.
A variant of the CRB-65 is the CURB. In this acronym the "U" stands for urea (urea-nitrogen) > 7 mmol/l. This score, however, requires a timely laboratory diagnosis.
LiteratureThis section has been translated automatically.
- Bauer TT et al. CRB-65 predicts death from community-acquired pneumonia. J Internal Med. 2006 260:93-101
- Dwyer R et al (2014) Improvement of CRB-65 as a prognostic tool in adult patients with community-acquired pneumonia. BMJ Open Respir Res 8: e000038.
- Ebell MH et al (2019) Meta-analysis of Calibration, Discrimination, and Stratum-Specific Likelihood Ratios for the CRB-65 Score. J Gene Internal Med 34:1304-1313.
- Frenzen FS et al. (2018) Admission lactate predicts poor prognosis independently of the CRB/CURB-65 scores in community-acquired pneumonia. Clin Microbiol Infect 24: 306.e1-306.e6.