Use use test

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Epicutaneous test procedure for clarifying an unclear or questionable test reaction to better assess clinical relevance. Modification of a " repeated open application test".

IndicationThis section has been translated automatically.

Assessment of the clinical relevance of sensitization to cosmetic ingredients using finished products.

ImplementationThis section has been translated automatically.

  • Application of the finished product 2 times/day for 1 week at a defined body area.
  • The chosen localisation should correspond to the normal application.
  • If possible, carry out a negative control: ideally a comparable product without the suspected allergen.
  • The test reaction is then evaluated according to the conditions of the standard epicutaneous test.
  • Indication of clinical relevance in the allergy certificate (see COADEX index below).

LiteratureThis section has been translated automatically.

  1. Villarama CD et al (2004) Correlations of patch test reactivity and the repeated open application test(ROAT)/provocative use test (PUT). Food Chem Toxicol 42: 1719-1725

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer