Smoker's leukoplakiaK13.2
DefinitionThis section has been translated automatically.
Oral leukoplakia due to heavy smoking, e.g. on the lips of pipe smokers. Special form: Leukokeratosis nicotinica palati.
General therapyThis section has been translated automatically.
Stop smoking immediately and without fail, six-monthly check-ups to exclude malignancies.
Internal therapyThis section has been translated automatically.
Therapy trial with isotretinoin (e.g. isotretinoin-ratiopharm; acne normin) 0.2-0.5 mg/kg bw/day or acitretin (neotigason) in a medium dosage of 30 mg/day is possible.
Operative therapieThis section has been translated automatically.
Excision in healthy people is therapy of choice. If malignant changes are bioptically ruled out,CO2 laser therapy, cryosurgery (2 cycles in open spray procedure or as contact procedure) or soft X-ray therapy (30-50 Gy, fractionated in 5 Gy doses) can be considered alternatively.
Progression/forecastThis section has been translated automatically.
Transition to spinocellular carcinoma possible.