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Leucokeratosis nicotinica palatiK13.2
Synonym(s)
HistoryThis section has been translated automatically.
Gruetz 1928
DefinitionThis section has been translated automatically.
Non-precancerous, exogenous-irritant callus formation of the palate in smokers.
EtiopathogenesisThis section has been translated automatically.
Chronic irritant effect of distillation products in tobacco smoke.
LocalizationThis section has been translated automatically.
Mostly at the hard, but also at the transition to the soft palate.
Clinical featuresThis section has been translated automatically.
Isolated or densely packed standing, paved appearing, grey-white, coarse, nodules of 0.1-0.3 cm diameter with dented or dotted reddish centre. These can confluent to larger plaques (up to 2.0-3.0 cm). The typical, regular dot-shaped patterns of the papules or plaques correspond to the salivary gland ducts. Pipe and cigar smokers may also experience a grey-brown or brown discolouration of the keratotic plaques (so-called smoker's melanosis).
HistologyThis section has been translated automatically.
Plump regular acanthosis with orthokeratotic keratinization. No cell atypia of the surface epithelium. No polarity loss. Clear fibrosis of the lamina propria.
TherapyThis section has been translated automatically.
Progression/forecastThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Farman AG et al (1977) Leukokeratosis nicotina glossi-smokers' tongue. Int J Oral surgery 6:340-347.
- Rodríguez I et al (1983) Prevalence of oral leukoplakia in Havana City, Cuba. Community Dent Oral Epidemiol 11:379-383.
- Saietz L (q1975) Prevalence of leukokeratosis nicotina palati among 3,819 danes. Community Dent Oral Epidemiol 3:80-85.