RashR21.x0

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 06.10.2023

Dieser Artikel auf Deutsch

Synonym(s)

Exanthema diseases; Exantheme; Rash; Skin rash

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

Exanthem" (from Gr. exantheo I blossom) refers to a group of infectious and non-infectious, inflammatory, temporary "skin rashes". Exanthemas are characterized by a dynamic, episodic course (either one episode or multiple episodes). They appear generalized or disseminated over larger areas, usually symmetrical(rubella, measles), rarely asymmetrical distribution (example: exanthema, unilateral laterothoracic in childhood). Exanthema is composed of different types of efflorescences (urticae, papules, vesicles, pustules). The dominant type is considered in a more detailed clinical description in the name: urticarial exanthema, macular exanthema, pustular exanthema and so on. If an exanthema course is characterized by multiple flare-ups, a "colorful" clinical aspect with different efflorescence types may appear (example: varicella exanthema).

In exanthemas in brown or black skin, the red tone of the efflorescences is absent. With a significantly more difficult diagnostic evaluation, other criteria such as anamnesis, symptomatology, distribution pattern, forms, surface design come to the forefront of the analytical evaluation.

ClassificationThis section has been translated automatically.

EtiopathogenesisThis section has been translated automatically.

Due to their morphology, some exanthema are characteristic of certain viral and bacterial infections (measles, scarlet fever). Others accompany as "parainfectious" exanthems various infectious diseases (e.g. Gianotti-Crosti syndrome). Exanthema also occurs in allergic, pseudoallergic and rheumatic diseases. Exanthems can be classified according to their etiology:

    • Infectious exanthema
      • Viral exanthema (most common form of exanthema in children)
      • Bacterial and other infectious exanthema
    • Parainfectious exanthema/enzyme defects
    • Allergic/pseudoallergic exanthema
    • Idiopathic exanthema
    • Exanthema for rheumatic diseases
    • Autoimmunological exanthema
    • Toxic exanthema
    • Pseudoexanthema caused by external infections

Efflorescence(s)This section has been translated automatically.

Exanthema can include all types of efflorescence. They usually show a synchronous monomorphism. A typical exception is varicella or PLEVA ( Pityriasis lichenoides et varioliformis acuta) with a synchronous polymorphism. Typical for varicella is the "starry sky" (several thrusts or continuous thrust activity over a longer period of time).

Differential diagnosisThis section has been translated automatically.

For practical reasons of differential diagnosis, exanthema diseases can also be classified according to their main age of manifestation:
  • neonatal exanthema
  • Exanthema in pre-school and school age
  • Adult exanthema.

Note(s)This section has been translated automatically.

  • When assessing an exanthema, the first and most important step towards a valid diagnosis is the basic distinction between an infectious and a non-infectious exanthema. Careful analysis of signs of infection such as fever, AZ disorder, lymphadenopathy, hepatosplenomegaly, blood count and the evaluation of an infection scenario can help here. Only after exclusion of an infectious exanthema can a non-infectious exanthema be considered. The most frequent infectious exanthema are viral exanthema.

LiteratureThis section has been translated automatically.

  1. Föster-Holst R (2007) Virus exanthema. dermatologist 55: 804-817

Authors

Last updated on: 06.10.2023