Glove-sock syndromeR21

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 23.02.2021

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Synonym(s)

Papular purple gloves and socks syndrome; PPGSS

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HistoryThis section has been translated automatically.

Harms, 1990

DefinitionThis section has been translated automatically.

Polyätiological, acral accentuated exanthema, which occurs associatively to viral infections.

EtiopathogenesisThis section has been translated automatically.

Associative exanthema in various viral diseases: primarily parvovirus B19 is associated, less frequently hepatitis B, cytomegalovirus, coxsackie B6, measles, rubella, HHV-6, HHV-7. Furthermore, PPGSS is associated with drugs(trimethoprim/sulfmethoxazole).

LocalizationThis section has been translated automatically.

Hands and feet.

Clinical featuresThis section has been translated automatically.

Acral accentuated exanthema of itchy, 2-4 mm large, isolated or even confluent red spots. The exanthema may be associated with fever, lymph node swelling and arthralgia.

LaboratoryThis section has been translated automatically.

Non-specific.

DiagnosisThis section has been translated automatically.

Clinical picture; clarification of an associated viral disease.

Differential diagnosisThis section has been translated automatically.

Gianotti-Crosti Syndrome

TherapyThis section has been translated automatically.

Symptomatic.

LiteratureThis section has been translated automatically.

  1. Alfadley A et al (2003) Papular-purpuric "gloves and socks" syndrome in a mother and daughter. J Am Acad Dermatol 48: 941-944
  2. Eijnden SV et al (2003) Gloves and socks lymphangitis associated with acute parvovirus B19 infection. Pediatric dermatol 20: 184-186
  3. Ghigliotti G et al (2000) Papular-purpuric gloves and socks syndrome in HIV-positive patients. J Am Acad Dermatol 43: 916-917
  4. Grilli R et al (1999) Papular-purpuric "gloves and socks" syndrome: polymerase chain reaction demonstration of parvovirus B19 DNA in cutaneous lesions and sera. J Am Acad Dermatol 41: 793-796
  5. Harms M et al (1990) Papular-purpuric "gloves and socks" syndrome. J Am Acad Dermatol 23: 850-854
  6. Smith SB et al (2002) Gloves and socks syndrome: early and late histopathologic features. J Am Acad Dermatol 47: 749-754
  7. Segui N et al (2000) Papular-purpuric 'Gloves-and-Socks' syndrome related to rubella virus infection. Dermatology 200: 89
  8. Tonelli S et al (2002) "Gloves and socks" papular purpuric syndrome following primary infection with parvovirus B19: a link between dermatologists and haematologists. Br J Haematol 117: 773-774

Authors

Last updated on: 23.02.2021

Author: Prof. Dr. med. Peter Altmeyer