Glove-sock syndrome R21

Harms, Feldmann 1990

Polyätiological, acral accentuated exanthema, which occurs associatively to viral infections.

Associative exanthema in various viral diseases: primarily parvovirus B19 is associated, less frequently hepatitis B, cytomegalovirus, coxsackie B6, measles, rubella, HHV-6, HHV-7. Furthermore, PPGSS is associated with drugs(trimethoprim/sulfmethoxazole).

Hands and feet.

Acral accentuated exanthema of itchy, 2-4 mm large, isolated or even confluent red spots. The exanthema may be associated with fever, lymph node swelling and arthralgia.

Non-specific.

Clinical picture; clarification of an associated viral disease.

Gianotti-Crosti Syndrome

Symptomatic.

1. Alfadley A et al (2003) Papular-purpuric "gloves and socks" syndrome in a mother and daughter. J Am Acad Dermatol 48: 941-944
2. Eijnden SV et al (2003) Gloves and socks lymphangitis associated with acute parvovirus B19 infection. Pediatric dermatol 20: 184-186
3. Ghigliotti G et al (2000) Papular-purpuric gloves and socks syndrome in HIV-positive patients. J Am Acad Dermatol 43: 916-917
4. Grilli R et al (1999) Papular-purpuric "gloves and socks" syndrome: polymerase chain reaction demonstration of parvovirus B19 DNA in cutaneous lesions and sera. J Am Acad Dermatol 41: 793-796
5. Harms M et al (1990) Papular-purpuric "gloves and socks" syndrome. J Am Acad Dermatol 23: 850-854
6. Smith SB et al (2002) Gloves and socks syndrome: early and late histopathologic features. J Am Acad Dermatol 47: 749-754
7. Segui N et al (2000) Papular-purpuric 'Gloves-and-Socks' syndrome related to rubella virus infection. Dermatology 200: 89
8. Tonelli S et al (2002) "Gloves and socks" papular purpuric syndrome following primary infection with parvovirus B19: a link between dermatologists and haematologists. Br J Haematol 117: 773-774