pseudoangioedema

Last updated on: 24.05.2025

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DefinitionThis section has been translated automatically.

Pseudoangioedema refers to acute swelling of the skin or mucosa that clinically resembles angioedema. They differ from these in their different etiopathogenesis, as they are not based on a histamine- or bradykinin-mediated mechanism.

ClinicThis section has been translated automatically.

Examples of non-histamine and bradykinin mediated pseudoangioedema are:

ACE angioedema ( T73.3) (captopril, enalapril, ramipril)
Sartan angioedema/sartans= At1 blockers (candesartan, losartan)
NSAIDs-angioedema (T73.3/e.g. aspirin)
mTOR inhibitor-induced angioedema (sirolimus, everolimus) (Beaini H et al.2024)
Tyrosine kinase inhibitors (e.g. dasatinib/Nyckowski T et al. 2022)
Antipsychotics (e.g. olanzapine/Malhotra M et al. 2013),
Neuroleptics such as risperidone (periorbial swelling/Pelizza L 2008)
Angioedema after biologics (e.g. dupilumab as an anti-IL4 receptor blocker)

Last updated on: 24.05.2025