Plexiform fibrohistiocytic tumor
Synonym(s)
Plexiform fibrohistiocytic tumor
HistoryThis section has been translated automatically.
Enzinger and Zhang 1988
DefinitionThis section has been translated automatically.
Preferably in children and young adults, fibro-myofibroblastically differentiated, slowly but locally aggressively growing, rarely metastatic, cutaneously-subcutaneously localized, painless tumor.
ManifestationThis section has been translated automatically.
Children and young adults, also appearing at a later age.
HistologyThis section has been translated automatically.
Tumor parenchyma arranged in baths and fascicles from fibroblastically or myofibroblastically differentiated spindle cell formations. Interspersed are epithelioid or histiocytic cells with multinucleated giant cells. Mitoses are rare. Also myxoid or fibrous sections. The tumor cells are immunoreactive for vimentin, CD68; negative for S-100 protein and pancytokeratin.
TherapyThis section has been translated automatically.
Excision with sufficient safety distance (danger of recurrence).
LiteratureThis section has been translated automatically.
- Elwood H et al (2011) Dermal and Subcutaneous Plexiform Soft Tissue Neoplasms. Surg Pathol Clin 4: 819-842.
- Harrill JC et al (2014) Plexiform fibrohistiocytic tumor of the foot: a case report. J Foot Ankle Surgery 53:635-637.
- Jacobson-Dunlop E et al (2011) Features of plexiform fibrohistiocytic tumor in skin punch biopsies: a retrospective study of 6 cases. At J Dermatopathol 33:551-556.
- Pissoat L et al (2011) Plexiform fibrohistiocytic tumor. Dermatologist 62: 809-812.
- Yalcinkaya U et al. (2013) Plexiform fibrohistiocytic tumor of bone. Pathol Int 63: 554-558.