Under Ozempic, see GLP1receptor agonists, there is a rapid breakdown of subcutaneous fatty tissue, including collagen and elastin in the facial area. The consequences are sunken facial areas, increased wrinkle formation and reduced skin elasticity, resulting in a prematurely aged appearance.
The main characteristics are sunken temples, increased dark circles under the eyes, bags under the eyes, protruding cheekbones due to loss of the buccal fat pad and shifting of tissue to the lower part of the face (sagging cheeks), wrinkling, particularly perioral and perinasal wrinkling, as well as a wrinkled neck.