Ophthalmic fuscocoeruleus nevusD22.30

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 12.10.2022

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Synonym(s)

mesodermal melanosis of the face and sclera; nevus of Ota; Nevus Ota; oculodermal melanocytosis; Oculodermal melanocytosis; Ota-Naevus

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HistoryThis section has been translated automatically.

Ota, 1939

DefinitionThis section has been translated automatically.

Mostly congenital dermal melanocytic nevus occurring almost exclusively in people of Mongolian descent, especially in women. An acquired variant has been described. See also naevus fuscocoeruleus deltoideoacromialis.

Occurrence/EpidemiologyThis section has been translated automatically.

Mostly performed by Asians. Common in Japan.

ManifestationThis section has been translated automatically.

Not always visible at birth. First manifestations are described up to the 10th LJ. Girls are 3-5 times more frequently affected than boys.

LocalizationThis section has been translated automatically.

Service area of the 1st and 2nd trigeminal branch.

Clinical featuresThis section has been translated automatically.

Integument: Irregular, light reddish-brown to blackish-bluish pigmentation corresponding to the Mongolian spot, half-sided in the cheek area along the trigeminal nerve innervation.

Optional development of papular or small-nodular, raised efflorescences. Involvement of the buccal mucosa is possible.

Extracutaneous manifestation: Involvement of the eye and the buccal mucosa is possible. Up to 26% of patients show bilateral manifestation. Involvement of the eardrum (55%), eyes (49%), nasal mucosa (28%), pharynx (24%) and palate (18%). Associated symptoms: glaucoma, cataract, deafness, occiput deformity, hemiatrophia facei.

HistologyThis section has been translated automatically.

In the middle and upper corium partly grouped, preferably periadnexial, spindle-shaped melanocytes filled with pigment granules, no melanophages.

TherapyThis section has been translated automatically.

If necessary, cosmetic cover (e.g. Dermacolor). Laser treatment sometimes leads to a brightening of the pigmentation. Clarification and monitoring of any accompanying symptoms.

Progression/forecastThis section has been translated automatically.

Rare development of a malignant melanoma. Intracerebral melanin-forming tumours possible.

LiteratureThis section has been translated automatically.

  1. Alvarez-Cuesta CC (2002) Nevus of Ota associated with ipsilateral deafness. J Am Acad Dermatol 47: S257-259
  2. Hidano A et al (1991) Acquired dermal melanocytosis of the face and extremities. Br J Dermatol 124: 96-99
  3. Kono T et al (2003) Use of Q-switched ruby laser in the treatment of nevus of ota in different age groups. Lasers Surg Med 32: 391-395
  4. Ota M, Tanino H (1939) Naevus fuscocaeruleus ophthalmo-maxillaris and melanosis bulbi. Tokyo Iji Shinshi 63: 1243-1245
  5. Terheyden P et al (2001) Nevus of Ota and choroid melanoma. dermatologist 52: 803-806
  6. Ueki H et al (1991) Acquired bilateral Naevus Ota. dermatologist 42: 584-586

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Last updated on: 12.10.2022