Oncogenesis, malignant melanoma
DefinitionThis section has been translated automatically.
The development of tumours is much more complex than initially assumed. Multiple point mutations, translocations, amplifications and deletions in genes probably contribute to the development of a tumour (see mutation below). There are also numerous epigenetic (see below epigenetics) changes.
ClassificationThis section has been translated automatically.
- MAP kinase signalling pathway: This pathway refers to a series of multi-step signal transduction pathways that are involved in the regulation of embryogenesis, cell differentiation, cell growth and programmed cell death, among other things.
- The high rate of mutations underlines their key role in the development of malignant melanoma. Chemically, these are protein kinases (molar mass 36-44 kDa), which phosphorylate other proteins at specific serine/threonine residues (serine/threonine kinases).