Listeriosis of the newbornP37.2
Synonym(s)
Granulomatosis infantiseptica; Newborn listeriosis; perinatal listeriosis
DefinitionThis section has been translated automatically.
Fetopathy caused by diaplacental infection with Listeria monocytogenes (gram-positive rod that is apathogenic for adults) with disseminated granulomas on the skin and in internal organs.
Occurrence/EpidemiologyThis section has been translated automatically.
Especially for premature babies.
Clinical featuresThis section has been translated automatically.
Skin symptoms: Disseminated, pinhead-sized, yellowish-white nodules on the entire integument surrounded by a red courtyard, see also listeriomas. Multiple organ symptoms due to granulomas in liver, lung, spleen, intestine, pharyngeal mucosa. Meningitis/Meningoencephalitis.
DiagnosisThis section has been translated automatically.
Pathogen detection from blood, liquor, throat swab, meconium, amniotic fluid. Serological diagnostics.
TherapyThis section has been translated automatically.
Pediatric intensive care. High-dose parenteral antibiotic therapy with combination of ampicillin and aminoglycosides. Dosage: Ampicillin (e.g. Binotal) 100-200 mg/kg bw/day i.v. in 2-4 ED, gentamicin (e.g. Refobacin) 5 mg/kg bw/day.
Progression/forecastThis section has been translated automatically.
Untreated infaust.
LiteratureThis section has been translated automatically.
- Benshushan A et al (2002) Listeria infection during pregnancy: a 10 year experience. Isr Med Assoc J 4: 776-780
- Gilbert GL (2002) 1: Infections in pregnant women. Med J Aust 176: 229-236
- Siegman-Igra Y et al (2002) Listeria monocytogenes infection in Israel and review of cases worldwide. Emerg Infect Dis 8: 305-310