Hidradenocarcinoma eccrinesC44.L9
Synonym(s)
Eccrine sweat gland carcinoma; Malignant eccrine hidradenoma; Nodular eccrine hidradenocarcinoma
DefinitionThis section has been translated automatically.
Rare malignant adnexal tumor.
ManifestationThis section has been translated automatically.
Mostly in older people.
LocalizationThis section has been translated automatically.
Face, lower extremity
Clinical featuresThis section has been translated automatically.
Mostly uncharacteristic, red, ulcerated node with aggressive growth behaviour. Tendency to visceral metastasis (bone, lung).
HistologyThis section has been translated automatically.
Asymmetrical carcinoma often developed at the base of a hidradenoma, which infiltrates the deeper parts of the dermis (and subcutis) in a broad-based manner. Tumour formations with net-like branched, very irregular structures. Tumor cells with bright cytoplasm. As in poroma formation, basaloid as well as light cytoplasmic parts. In places, spindle-cell differentiated cell sections are also possible. Plenty of mitoses. Proof of mass necrosis.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Surgically with safety margin according to the guidelines for spinocellular carcinoma. Sentinel lymph node biopsy required.
LiteratureThis section has been translated automatically.
- Bogner PN et al (2003) Lymphatic mapping and sentinel lymph node biopsy in the detection of early metastasis from sweat gland carcinoma. Cancer 97: 2285-2289
- Khalil HM et al (2003) Malignant eccrine hidradenoma of neck causing acute heart failure. Auris nasus larynx 30: 307-310
- Lim SC et al (1998) Giant hidradenocarcinoma: a report of malignant transformation from nodular hidradenoma. Catholic Int 48: 818-823
- Park HJ et al (2000) Nodular hidradenocarcinoma with prominent squamous differentiation: case report and immunohistochemical study. J Cutan cathode 27: 423-427