Granuloma anulare multiformeL92.8

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

Granuloma anulare multiforme; Granuloma multiforme; Mkar disease; Mkar Disease; Nkanu disease

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HistoryThis section has been translated automatically.

Leiker, 1964

DefinitionThis section has been translated automatically.

A chronic, granulomatous skin disease of unknown etiology, frequently occurring in Central Africa. Possibly identical with actinic granuloma.

Occurrence/EpidemiologyThis section has been translated automatically.

Especially in Central and East Africa.

ManifestationThis section has been translated automatically.

Mostly adults, gynecotropia.

LocalizationThis section has been translated automatically.

Mainly arms and hands, upper torso, head.

Clinical featuresThis section has been translated automatically.

Rough skin-colored papules confluent to polycyclic foci with central healing and depigmentation. Initial itching, otherwise without symptoms.

HistologyThis section has been translated automatically.

Circumscribed necrobiosis foci in the corium with peripheral histiocytic border wall and numerous giant cells.

Differential diagnosisThis section has been translated automatically.

Leprosy, granuloma anulare; sarcoidosis; tuberculosis cutis luposa; granulomatosis disciformis chronica et progressiva.

TherapyThis section has been translated automatically.

No useful therapy modalities are known.

Progression/forecastThis section has been translated automatically.

Eminently chronic disease with a course lasting months to years. Spontaneous healing after years is described.

LiteratureThis section has been translated automatically.

  1. Garrett AS (1999) Granuloma multiforme (called Nkanu disease in the 1940s and Mkar disease in 1964) Int J Lepr Other Mycobact Dis 67: 172-174
  2. Krampitz HE (1967) Granuloma multiforme Leiker. dermatologist 18: 365-368
  3. Leiker DL et al (1964) Granuloma multiforme. A new disease resembling leprosy. Int J Lepr 32: 368-370.
  4. Rogge T (1977) Granuloma multiforme. Dermatologist 28: 375-377

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer