Creams ambiphile (overview)
Synonym(s)
DefinitionThis section has been translated automatically.
Creams that represent a transition between hydrophobic creams and hydrophilic creams. They have a bicoherent structure of hydrophilic and lipophilic phase and contain relatively high amounts of oil-in-water emulsifiers as well as water-in-oil emulsifiers. Without breaking the emulsion system, larger quantities of water as well as lipophilic substances can be incorporated, whereby an O/W or W/O emulsion system is formed with sliding transitions. They are almost universally applicable in the formulation.
Pharmacodynamics (Effect)This section has been translated automatically.
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IncompatibilityThis section has been translated automatically.
- In ambiphilic creams containing non-ionic emulsifiers with a hydrophilic polyethylene glycol portion, the incorporation of phenolic substances may lead to a loss of efficacy or even to the breaking of the emulsion depending on their concentration.
- Inhomogeneities can be caused by active substances such as benzalkonium chloride, benzyl alcohol, cetylpyridinium chloride, chlorocresol, hexachlorophene, β-naphthol, nipagine, oleum thyme, phenol. liquefact., Pix betulin., Pix juniper., Pix lithanth., polidocanol, pyrogallol, resorcinol, salicylic acid, tannin, tetracaine HCl and tyrothricin.
- Colour changes can be caused by dithranol, oxytetracycline-HCl, silver nitrate and tetracycline-HCl.
- Chloramine T leads to an odour change.
Recipe(s)This section has been translated automatically.
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Compatibility of drugs in ambiphilous creams
Acridine flavinium chloride 2% |
Dexpanthenol 5% |
Sodium chloride 10 |
allantoin 0,5% |
Dimetine maleate 1% |
neomycin sulfate 0,5%. |
aluminium chloride 10% |
Dimeticone 10% |
Nicotinic acid benzyl ester 3%. |
Ammonium bituminosulphonate 10 |
Diphenhydramine HCl 2% |
nitrofurazone 0,2% |
Amphotericin B 3% |
Erythromycin 2% |
Nystatin 100 000 IU/g |
anthrarobin 2% |
Ethacridine lactate 1% |
Oleum Pini 1,5 |
azulene 0,2% |
Eucalyptol 10% |
Pheniramine hydrogen maleate 1,25% |
bacitracin 500 IU/g |
Gentamicin sulphate 0,2 |
Polyvidon iodine 10% |
Bamipine HCl 2% |
Urea 10% Urea |
Procaine HCl 2% |
Benzoic acid 5% |
Hydrarg. sulf. rubr. 1% |
Sulphur 5% |
Benzoyl peroxide 5% |
hydrocortisone 1% |
Sorbic acid 0,1% of |
betamethasone-17-valerate 0,1% |
hydroxyquinoline sulfate 0,5%. |
Sulphadiazine 5% |
Bufexamac 5% |
potassium iodide 3,5%. |
sulfisomidine 5% |
calcium chloride 5% |
Camphor 5% |
terpiniol 1,5 |
Chloramphenicol 1% |
Cod liver oil 10% |
Tinctura Myrrh 3% |
Chlorophenoxamine-HCl 1,5% Chlorophenoxamine-HCl 1,5% Chlorophenoxamine |
Liq. alum. acet. 20% |
tretinoin 0.1% |
Chlortetracycline HCl 3% |
Liq. carb. deterg. 10% |
triamcinolone acetonide 0,1 |
Chrysarobin 5% |
Menthol 5% |
Undecylenic acid 5% |
Clioquinol 5% |
Merbromine 2% |
Zinc oxide 10 |
clotrimazole 1% |
Methyl salicylate 5% |
Zinc undecylenate 5% |
dexamethasone 0,1% |
Lactic acid 5 |
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