Atovaquon

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Half-lifeThis section has been translated automatically.

> 50 h

IndicationThis section has been translated automatically.

Pneumocystis carinii pneumonia or toxoplasmosis in AIDS patients(replacement preparation especially for glucose-6-phosphate dehydrogenase deficiency).

Dosage and method of useThis section has been translated automatically.

3 times 750 mg/day p.o. during meals.

Undesirable effectsThis section has been translated automatically.

Nausea, diarrhoea, allergic reactions, headaches, vomiting, insomnia, increase in transaminases and amylases, anemia.

InteractionsThis section has been translated automatically.

See Table 1.

ContraindicationThis section has been translated automatically.

Pregnancy, nursing.

PreparationsThis section has been translated automatically.

Wellvone

TablesThis section has been translated automatically.

Essential interactions of Atovaquon

Aciclovir

Atovaquon plasma mirror ↓

Benzodiazepines

Atovaquon plasma mirror ↓

Cephalosporins

Atovaquon plasma mirror ↓

Fluconazole

Atovaquon plasma mirror ↓

Metoclopramide

Atovaquon plasma mirror ↓

Opiates

Atovaquon plasma mirror ↓

Paracetamol

Atovaquon plasma mirror ↓

Prednisolone

Atovaquon plasma mirror ↑

Rifampicin

Atovaquon plasma mirror ↓ by 50% ↓

Zidovudine (AZT)

Atovaquon ↑ Plasma level by 35%

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Last updated on: 29.10.2020