Antiprotozoal agents

Author:Prof. Dr. med. Peter Altmeyer

Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Medicines effective against protozoa, see Table 1.

TablesThis section has been translated automatically.

Overview of antiprotozoal agents and their indication

	Pathogen	Active substance
amoebas	Acanthamoeba spp.	Amphotericin B, sulfonamides, for keratitis: Neomycin
	Dientamoeba fragilis	possibly metronidazole
	endolimax nana	no therapy necessary
	entamoeba coli	no therapy necessary
	histolytic entamoeba	Metronidazole
	Negleria fowleri	Amphotericin B (possibly + rifampicin or miconazole)

Ciliates	Balantidium coli	tetracycline, metronidazole

Flagellates	Chocolomastix mesnii	possibly metronidazole
	Giardia lamblia	Metronidazole
	Leishmania braziliensis complex	Antimony preparations, pentamidine
	Leishmania donovani complex	Antimony preparations, pentamidine
	Leishmania tropica	Antimony preparations
	vaginal trichomonas	Metronidazole
	Trypanosoma br. gambiense, rhodiense I, II	Suramin or Pentamidine
	Trypanosoma br. gambiense, rhodiense III	Melarsoprol
	Trypanosoma cruzi	Nifurtimox

Sporozoen	Babesia spp.	Diamidine, clindamycin and/or quinine
	Cryptosporidium spp.	Spiramycin
	Plasmodium spp.	chloroquine, mefloquine, quinine, possibly primaquine
	pneumocystis carinii	clindamycin/pentamidine or trimethoprim/sulfamethoxazole
	Sarcocystis spp.	possibly sulfonamides
	toxoplasma gondii	Sulphonamides, clindamycin or sulphonamides or pyrimethamine or spiramycin

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer