Amorolfin

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Topical antimycotic. Only morpholine derivative used in human medicine.

Pharmacodynamics (Effect)This section has been translated automatically.

Fungistatic and fungicidal through intervention in the synthesis of ergosterol.

IndicationThis section has been translated automatically.

Mycoses caused by dermatophytes and yeasts in case of an infestation < 80% of the nail surface, especially in case of distal infestation. S.a. Tinea corporis, tinea pedum, cutaneous candidiasis, tinea unguium.

Dosage and method of useThis section has been translated automatically.

  • Creams / Ointments: Apply once a day in the evening.
  • Nail varnish: Apply 1-2 times a week to affected nails, file nails regularly.

Standard concentrationThis section has been translated automatically.

  • Creams and ointments: 0.25%.
  • Nail polish: 5%.

Undesirable effectsThis section has been translated automatically.

Allergic reactions, burning, pruritus.

ContraindicationThis section has been translated automatically.

Amorolfine hypersensitivity, children, infants (lack of clinical experience), pregnancy, lactation.

PreparationsThis section has been translated automatically.

Loceryl Nail Polish/Cream.

LiteratureThis section has been translated automatically.

  1. Chandra S et al (2019) A Randomized, Double-blind Study of Amorolfine 5% Nail Lacquer with Oral Fluconazole Compared with Oral Fluconazole Alone in the Treatment of Fingernail Onychomycosis. Indian J Dermatol 64:253-260.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer