Ribes nigrum leaf extract (inci)
Synonym(s)
DefinitionThis section has been translated automatically.
Ribes nigrum leaf extract is the extract from the leaves of Ribes nigrum, the black currant, a shrub from the saxifrage family that grows up to 2 meters high. Ribes nigrum fruit extract is used in cosmetic formulations. The extract softens and smoothes the skin.
The leaf extract also has a perfuming effect (improves the smell of a product and/or perfumes the skin).
Pharmacodynamics (Effect)This section has been translated automatically.
Leaf extracts of Ribes nigrum L. (blackcurrant/RNLE) have been shown to have positive effects on inflammatory diseases due to their high content of flavonols and anthocyanins. Ribes nigrum L. preferentially interferes with IFN-γ signaling. This effect has been attributed to flavonols, which may also be responsible for the ability of RNLE to interfere with TNF-alpha/IL-4-induced TSLP release in a cAMP-independent manner. These results suggest that RNLE may have an anti-allergic effect that is mediated in keratinocytes via mechanisms beyond the involvement of histamine.
LiteratureThis section has been translated automatically.
- Magnavacca A et al. (2021) Ribes nigrum Leaf Extract Preferentially Inhibits IFN-γ-Mediated Inflammation in HaCaT Keratinocytes. Molecules 26:3044.