Images (1)
Eugenol
Synonym(s)
DefinitionThis section has been translated automatically.
Substance that is used as a fragrance and flavoring agent. It is also used in medicines and in dentistry. Eugenol is the main component of clove oil which is widely used in dentistry (e.g. also in root canal treatment). The substance is represented as a relevant allergen in the epicutaneous test series"fragrance mix".
Undesirable effectsThis section has been translated automatically.
Eugenol and Isoeugenol play an important role as allergens. Sensitizing potency: Medium. Frequency of sensitization: Occasional. Sensitization ( contact allergy; urticaria) is mainly found on dental material by dental staff. Cross-reactivity exists to Peru Balsam. Clove oil also seems to have an antimycotic and antibacterial effect. Even today it is still a standard agent for tooth root fillings.
The DKG has so far tested clove oil 2% in Vaseline. This application form is no longer available as a test substance in Germany. Therefore, the test substance Eugenol 1% in Vaseline is now (as of 2016) recommended. Clove oil consists of 90% eugenol, which is also contained in the fragrance mix.
LiteratureThis section has been translated automatically.
- Kamyab AA et al (2013) Anti-Inflammatory, gastrointestinal andhepatoprotective effects of Ocimum sanctum Linn: an ancient remedy with newapplication. Inflammatory Allergy Drug Targets 12:378-384
- Tammannavar P et al (2013) An unexpected positivehypersensitive reaction to eugenol. BMJ Case Rep18 doi: 10.1136/bcr-2013-009464.