Angioedema acquired/mast cell degranulationT73.3
DefinitionThis section has been translated automatically.
Acquired angioedema at the bottom of a mast cell degranulation. Mostly at the base of a type I reaction or intolerance reaction to protein components in food and drugs (especially salicylates, preservatives) as well as physical stimuli (vibration, pressure), often the etiology remains unclear.
TherapyThis section has been translated automatically.
- Cooling. If triggered by medication, discontinue medication. Glucocorticoids such as prednisolone (e.g. Solu-Decortin H) initial 250 mg i.v., for severe reactions up to 1.0 g/day i.v. Gradual reduction depending on the clinic. In emergency situations, the administration of a drinking cortisone (Celestamine N liquidum) has proven to be effective. This can be prescribed to patients with known and recurrent angioedema.
- Additionally, antihistamines such as dimetinden (e.g. Fenistil) initially 1-2 amp/day i.v., reduction according to clinic. In case of complications such as laryngeal edema, glottis edema, immediate intensive care measures! For emergency situations, use a ready-to-use adrenaline syringe(e.g. Anapen, Fastject).