Protein z defectsD68.-

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Polymorphisms of the protein Z and disturbances of the protein Z-dependent protease lead to an increased tendency to thrombosis and more often to apoplexies.

EtiopathogenesisThis section has been translated automatically.

Protein Z acts as a cofactor for the binding of thrombin to the phospholipid surface, thus promoting clotting. On the other hand, it is involved in the degradation of F-Xa. If this function is disturbed, it can lead to an increased tendency to thrombosis and apoplexies.

LiteratureThis section has been translated automatically.

  1. HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin S. 231.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer