Plasmine/plasminogen deficiency

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

This is a congenital, autosomal-recessive inherited deficiency of plasminogen, the precursor of plasmin. Due to this deficiency, too little plasmin is available for endogenous fibrinolysis. There may also be genetic defects in the plasmin that lead to reduced functions (dys-forms). Many genetic variants of such plasminogen mutations have been described, named after the cities of their discovery.

Occurrence/EpidemiologyThis section has been translated automatically.

This defect is found in 2-3% of young patients with deep vein thrombosis.

LiteratureThis section has been translated automatically.

  1. HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin S. 232.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer