Cmax - Altmeyers Encyclopedia - Department Pharmacology-Toxicology

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Keywords This section has been translated automatically.

Tmax; AUC;

Definition This section has been translated automatically.

_Cmax (maximum plasma concentration): In pharmacokinetics,_Cmax refers to the highest concentration of a drug reached in blood plasma after its administration.

Pharmacokinetic significance:

-_Cmax: The maximum measured plasma concentration of a drug (e.g., ng/ml).

-_Tmax: The time at which Cmax is reached.

- AUC (Area Under the Curve): Area under the concentration-time curve; a measure of total systemic drug exposure.

-_{t½ (}elimination half-life): The time it takes for the plasma concentration to decrease by 50% during the terminal elimination phase.

Last updated on: 31.10.2026