Shiitake

Last updated on: 15.06.2025

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DefinitionThis section has been translated automatically.

Edible mushroom, originally from Asia, which is also increasingly used in Europe. It has been used as a medicinal mushroom in Chinese medicine for thousands of years, also in Japan, and is also known as the king of medicinal mushrooms.

Shiitake grows on various deciduous trees, has a light to dark brown cap and deep lamellae.

As a food, the flavor with the taste"umami" (=Japanese for delicious) is popular. Umami is recognized as a fifth flavour alongside sweet, sour, salty and bitter.

No monograph.

In Asia, shiitake is valued for arteriosclerosis, diabetes, high blood pressure and for the treatment of malignant tumors, as well as for stomach ulcers, neuralgia, constipation and gout, and as an anti-aging agent.

Studies have shown efficient bioactivity against breast cancer, lung cancer and colon cancer.

In a randomized, double-blind, placebo-controlled study with 68 patients (Spim et al. 2021), a 10% reduction in triglycerides and biomarkers for oxidative stress was demonstrated after 66 days. However, 10% of patients suffered from shiitake dermatitis.

Further studies indicate a reduction in blood sugar.

Rarely gastrointestinal complaints occur, described with eosinophilia, casuistically also obstruction in the ileum, sometimes with indication for surgery. The obstruction is due to the high proportion of insoluble fiber in the mushroom: shiitake consists of 49.1 % fiber, 82.9 % of which is insoluble fiber. The soft, slippery texture of the mushroom leads to accidental swallowing without sufficient chewing.

LiteratureThis section has been translated automatically.

  1. Spim SRV et al. (2021) Effects of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Bars on Lipid and Antioxidant Profiles in Individuals with Borderline High Cholesterol: A Double-Blind Randomized Clinical Trial. Int J Med Mushrooms. 23(7):1-12. doi: 10.1615/IntJMedMushrooms.2021038773. PMID: 34375514.
  2. Tamang B et al- (2022) Astragalus Shiitake-A Novel Functional Food with High Polysaccharide Content and Anti-Proliferative Activity in a Colorectal Carcinoma Cell Line. Nutrients. 2;14(11):2333. doi: 10.3390/nu14112333. PMID: 35684133; PMCID: PMC9182587.
  3. Levy AM et al. (1998) Eosinophilia and gastrointestinal symptoms after ingestion of shiitake mushrooms. J Allergy Clin Immunol. ;101(5):613-20. doi: 10.1016/S0091-6749(98)70168-X. PMID: 9600497.
  4. Miyagishima D et al. (2022) Bowel Obstruction due to Shiitake Mushrooms: Diagnostic Features on Computed Tomography. Intern Med. 2022 Nov 15;61(22):3349-3354. doi: 10.2169/internalmedicine.9181-21. Epub 23. PMID: 35466167; PMCID: PMC9751717.
  5. Tan J et al. (2019) Two cases of small bowel obstruction due to a shiitake mushroom. Gastroenterol Rep (Oxf);7(4):298-300. doi: 10.1093/gastro/gox028. Epub 2017 Jul 26. PMID: 31413838; PMCID: PMC6688735.
  6. Ng GH et al. (2020) A case series of intestinal obstruction secondary to shiitake mushroom intake during Chinese New Year. J Surg Case Rep. 14;2020(10):rjaa328. doi: 10.1093/jscr/rjaa328. PMID: 33093939; PMCID: PMC7566373.
  7. Chakraborty S et al. (2023) Lentinan, β-glucan from Shiitake (Lentinula edodes): A review on structure, conformational transition, and gastro-intestinal interaction contributing towards its anti-diabetic potential, Trends in Food Science & Technology, 142, 104224, https://doi.org/10.1016/j.tifs.2023.104224.
  8. Levy AM et al. (1998) Eosinophilia and gastrointestinal symptoms after ingestion of shiitake mushrooms. J Allergy Clin Immunol. ;101(5):613-20. doi: 10.1016/S0091-6749(98)70168-X. PMID: 9600497.

Last updated on: 15.06.2025