Santonin

Last updated on: 15.06.2025

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DefinitionThis section has been translated automatically.

Important ingredient of Artemisia cina, the so-called worm seed, forms white, odorless and tasteless crystals.

Pfizer's first commercially successful medicinal substance 170 years ago.

Note: Karl Pfizer and his cousin Charles F. Erhart, who came from Ludwigsburg, founded Charles Pfizer & Company in Brooklyn, New York in 1849 with an antiparasitic agent: Santonin. This was formerly used against roundworms, but is now obsolete due to its toxicity.

LiteratureThis section has been translated automatically.

  1. https://www.dw.com/de/pfizer-held-und-profiteur-der-pandemie/a-56603820
  2. Sakipova Z et al. (2017) Quantification of santonin in eight species of Artemisia from Kazakhstan by means of HPLC-UV: Method development and validation. PLoS One 16;12(3):e0173714. doi: 10.1371/journal.pone.0173714. Erratum in: PLoS One. 2017 Mar 28;12(3):e0175088. doi: 10.1371/journal.pone.0175088. PMID: 28301522; PMCID: PMC5354383.

  3. Sakipova Z et al. (2020) Pharmacological Evaluation of Artemisia cina Crude CO2 Subcritical Extract after the Removal of Santonin by Means of High Speed Countercurrent Chromatography. Molecules. 12;25(12):2728. doi: 10.3390/molecules25122728. PMID: 32545512; PMCID: PMC7355858.

Last updated on: 15.06.2025