Ononidis radix

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Synonym(s)

Hauhechel Root; Uricaria root

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DefinitionThis section has been translated automatically.

Ononidis Radix, the Hauhechel root, is a herbal medicine with diuretic effect, which is used internally for the treatment of urinary tract infections (cystitis). Ononidis Radix, according to Ph.Eur., consists of the whole or the cut, dried root of Ononis spinosa L., the thorny bark hedge.

IngredientsThis section has been translated automatically.

Extracts of the Hauhechel root contain 0.1% essential oil (with trans-anethole), Onocol also called alpha-onocerine, a triterpene which has an acetylcholinesterase inhibitory activity, the isoflavone glycosides (ononine, trifolirhizin) as well as tanning agents.

Field of application/useThis section has been translated automatically.

The dried root is traditionally used as a diuretic for flushing therapy in uncomplicated infections and inflammations of the urinary tract (urinary tract infections). It is also said to prevent deposits of kidney gravel and urinary stones.

Recipe(s)This section has been translated automatically.

2 heaped teaspoons of Hauhechel root are brewed with 150 ml boiling water and left to rest for about 30 minutes. Then pour off through a tea strainer. Unless otherwise prescribed, 1 cup is drunk 2 to 3 times/day between meals.

LiteratureThis section has been translated automatically.

  1. Daruházi AE et al (2008) Utility of cyclodextrins in the formulation of genistein part 1 Preparation and physicochemical properties of genistein complexes with native cyclodextrins. J Pharm Biomed Anal 48:636-640.
  2. Hilp K et al (1975) Constituents from Ononis spinosa L. 1 Volatile Oil of the radix Ononidis. Arch Pharm (Weinheim) 308:429-433.
  3. Joksić G et al.(2003) Antibacterial medicinal plants Equiseti herba and Ononidis radix modulate micronucleus formation in human lymphocytes in vitro. J Environ Pathol Toxicol Oncol 22:41-48.
  4. Orhan I et al(2003) Alpha-onocerine: an acetylcholinesterase inhibitor from Lycopodium clavatum. Planta Med 69(3):265-267.
  5. Rowan MG et al,(1971) The enzymic conversion of squalene, 2(3),22(23)-diepoxides to alpha-onocerine by a cell-free extract of Ononis spinosa.FEBS Lett 12:229-232.

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Last updated on: 29.10.2020