Menyanthidis folium

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 12.10.2022

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Synonym(s)

Blue Clover; Dark Clover Leaves; fever clover; Marsh clover; Menyanthes trifolium

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DefinitionThis section has been translated automatically.

Bitter clover leaves, also known as Menyanthidis folium, is a drug used as a herbal remedy or bittering agent and is used for internal use in loss of appetite and indigestion.

HMPC monograph: Traditional-use: Loss of appetite, mild indigestion, flatulence, flatulenceESCOP monograph
: Loss of appetite, indigestion, dyspeptic complaints, biliary complaintsCommission
E monograph: Loss of appetite, indigestion (dyspeptic complaints).

IngredientsThis section has been translated automatically.

Dark clover leaves contain flavonoids, tannins, dimeric glycosidic-iridoid bitter substances and essential oil. The bitter value must always be at least 3000.

EffectsThis section has been translated automatically.

The ingredients of Menyanthidis folium promote the secretion of gastric juice and saliva.

Field of application/useThis section has been translated automatically.

Menyanthidis folium is used for existing dyspeptic complaints and loss of appetite. It is also used for gallbladder and bile duct complaints.

DosageThis section has been translated automatically.

The usual daily dose corresponds to 1.5 to 3.0 g of the drug and is used as tea infusion (Commission E).

Undesirable effectsThis section has been translated automatically.

may cause nausea, vomiting and diarrhea at high doses

Note(s)This section has been translated automatically.

Bitter clover leaves are less effective than the gentian root or an Extractum centaurii (centaury).

LiteratureThis section has been translated automatically.

  1. Junior P (1989) Further investigations regarding distribution and structure of the bitter principles from Menyanthes trifoliata. Planta Med 55:83-87.
  2. Schilcher H (2016.) Leitfaden Phytotherapie. Urban & Fischer Verlag Munich p. 80 f.
  3. https://arzneipflanzenlexikon.info/bitterklee.php.
  4. Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 82-83
  5. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-menyanthes-trifoliata-l-folium_en.pdf

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Last updated on: 12.10.2022