M. haemophilum can be isolated from superficial skin lesions, bronchopulmonary specimens, or blood in immunocompromised patients (Lindeboom JA et al. 2011). Detection is difficult because the germ only grows at 31 °C and very slowly and, in addition, requires the addition of iron to the medium.
Mycobacterium haemophilum
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The skin symptoms are relatively uncharacteristic and are observed in the context of a systemic infection. Nodular and ulcerative lesions may occur in immunocompetent as well as immunocompetent patients (Jurairattanaporn N et al. 2020). Furthermore, infections of the sclera (scleritis) have been described (Pisitpayat P et al. 2020).
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Reliable resistance determination is not possible due to limited growth. According to ATS/IDSA, there is in vitro sensitivity to RMP, rifabutin, clarithromycin, FQ and amikacin (Griffith DE et al. 2007). Lindeboom et al. recommend a combination of clarithromycin, ciprofloxacin, and an antibiotic from the rifamycin group.
LiteratureThis section has been translated automatically.
- Griffith DE et al (2007) Am J Respir Crit Care Med 175: 367-416.
- Jurairattanaporn N et al (2020) Mycobacterium haemophilum skin and soft tissue infection in a kidney transplant recipient: A case report and summary of the literature. Transpl Infect Dis 22:e13315.
- Lindeboom JA et al (2011) Clinical manifestations, diagnosis, and treatment of Mycobacterium haemophilum infections. Clin Microbiol Rev 24: 701-717.