TNF receptor-associated periodic fever" is a hereditary inflammatory disease characterized by recurrent fever episodes combined with abdominal discomfort, arthralgia, conjunctivitis and periorbital oedema as well as a generalized maculo-papular exanthema associated with autosomal dominant inherited mutations of the TNFRSF1A gene (gene locus: 12p13.2). For further entities see below. TRAPS.