STA1-gene

Last updated on: 13.07.2021

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DefinitionThis section has been translated automatically.

STAT1 is the acronym for "Signal Transducer And Activator Of Transcription 1" is a protein coding gene located on chromosome 2q32.2. The gene product of the same name, signal transducer and activator of transcription 1, mediates cellular responses to interferons (IFNs).

Diseases associated with STAT1 include the immunodeficiency syndromes 31A and 31B/C. An important paralog of the STAT1 gene is STAT4.

Last updated on: 13.07.2021