Rare genetic form of hypertension characterized by hyperkalemia, mild hyperchloremic metabolic acidosis, normal or elevated aldosterone, low renin, with normal renal glomerular filtration rate (GFR).
Pseudohypoaldosteronism type 2I15.1
DefinitionThis section has been translated automatically.
Occurrence/EpidemiologyThis section has been translated automatically.
The prevalence of the disorder is unknown. To date, slightly more than 180 affected individuals and families have been described in the literature.
Clinical featuresThis section has been translated automatically.
Hypertension in adulthood; furthermore, hyperkalemia, mild hyperchloremic acidosis, and low renin are present at a young age and are constant findings.
Aldosterone levels may be normal to high. Hypervolemia is frequently observed. Growth failure has been described in some cases. Patients do not present with renal failure.